Culture conditions for production of biomass, adenosine, and cordycepin from Cordyceps sinensis CS1197: Optimization by desirability function method
نویسندگان
چکیده
منابع مشابه
Optimization of Large-Scale Culture Conditions for the Production of Cordycepin with Cordyceps militaris by Liquid Static Culture
Cordycepin is one of the most important bioactive compounds produced by species of Cordyceps sensu lato, but it is hard to produce large amounts of this substance in industrial production. In this work, single factor design, Plackett-Burman design, and central composite design were employed to establish the key factors and identify optimal culture conditions which improved cordycepin production...
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Cordycepin (3’-deoxyadenosine) is one of the most versatile metabolites of Cordyceps militaris due to its broad spectrum of biological activity. In this study, response surface methodology (RSM) was applied to optimize the medium components for the cordycepin production by submerged liquid culture. The optimal parameters for cordycepin production within the experimental range of the variables r...
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Cordycepin, a nucleoside derivative, is an active component of parasitic fungus, Cordyceps militaris which has been known for many pharmacological activities. The present study was carried out to develop an extraction strategy for cordycepin and to evaluate its antimicrobial potential. Solventsolvent extraction method was used to extract cordycepin from liquid culture of C. militaris. Crude con...
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Cordycepin (3′-deoxyadenosine) exhibits antimicrobial, anticancer, antimetastatic, immunomodulatory and insecticidal effects, and is one of the most important bioactive anticancer agents found in Cordyceps species (summer grass-winter worm). However, due to the requirements of specific hosts and strict growth environments, Cordyceps militaris is very scarce in nature. Therefore, the production ...
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Cordyceps is a fastidious pathogenic fungus infecting insects, and recent years have witnessed rapid progress in its medical properties. In this study, a wild isolate, C. cicadae MP12, was characterized through in vitro cultivation and its nuclear small-subunit (SSU) ribosomal DNA (rDNA) data. In vitro culture of C. cicadae MP12 was established by growing its fruiting bodies in a solid matrix. ...
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ژورنال
عنوان ژورنال: Pharmacognosy Magazine
سال: 2015
ISSN: 0973-1296
DOI: 10.4103/0973-1296.168946